Medicare Part D drug coverage guides
Coverage, cost, and alternatives for 25 of the most prescribed drugs on Medicare in 2026.
Medicare Part D covers most prescription drugs, but coverage details — what tier the drug is on, how much you'll pay, and any restrictions like prior authorization — vary widely between plans. Below are coverage guides for 25 of the most prescribed medications on Medicare.
Drugs marked with 🟦 are subject to Medicare's negotiated prices under the Inflation Reduction Act, with reduced prices effective January 1, 2026.
Diabetes and weight management
Heart and blood pressure
Asthma and COPD
Autoimmune conditions (specialty)
Other commonly prescribed
Don't see your medication?
The drugs listed here are some of the most commonly searched, but Medicare Part D covers thousands of medications. To check coverage for any specific drug, use the Medicare.gov Plan Finder with your medication list and ZIP code.
Compare your Part D options
Coverage and costs for this drug vary significantly between plans. Compare your options:
You can also visit Medicare.gov or call 1-800-MEDICARE