10 drugs with Medicare-negotiated prices for 2026
For the first time, Medicare negotiated directly with drug companies to lower prices on 10 of the most expensive Part D medications. These new prices took effect January 1, 2026.
The 10 drugs with new lower prices
All Part D plans are required to cover these drugs at or below the negotiated prices. The discounts range from 38% to 79% off the 2023 list prices.
| Drug | Treats | 2023 list price (30-day) | 2026 negotiated price | Discount |
|---|---|---|---|---|
| Januvia | Type 2 diabetes | $527 | $113 | 79% |
| NovoLog/Fiasp | Diabetes (insulin) | $495 | $119 | 76% |
| Farxiga | Diabetes, heart failure, CKD | $556 | $178 | 68% |
| Enbrel | Rheumatoid arthritis, psoriasis | $7,106 | $2,355 | 67% |
| Jardiance | Type 2 diabetes, heart failure | $573 | $197 | 66% |
| Stelara | Crohn's disease, psoriasis | $13,836 | $4,695 | 66% |
| Xarelto | Blood clots, stroke prevention | $517 | $197 | 62% |
| Eliquis | Blood clots, stroke prevention | $521 | $231 | 56% |
| Entresto | Heart failure | $628 | $295 | 53% |
| Imbruvica | Blood cancers | $14,934 | $9,319 | 38% |
Source: CMS Medicare Drug Price Negotiation Program. List prices are 2023 Wholesale Acquisition Cost (WAC) for a 30-day supply. Negotiated prices (Maximum Fair Prices) effective January 1, 2026.
How this affects your costs
The negotiated prices set the maximum amount that Part D plans pay manufacturers. Your actual out-of-pocket cost depends on your specific plan's formulary, cost-sharing structure, and which coverage phase you're in. However, because plans are paying less for these drugs, your copays and coinsurance should be lower too.
If you take any of these medications, it's worth comparing Part D plans to see which one offers the best deal for your specific drugs.
Take one of these drugs? Check your plan
Not all plans pass the savings through equally. Comparing plans by your specific medications can reveal significant cost differences. Your state's SHIP counselor can help for free, or you can compare plans on PlanMatch.com.
More drugs coming in 2027 and beyond
This is just the beginning. Negotiated prices for 15 additional drugs will take effect in 2027, including popular medications like Ozempic. Up to 15 more drugs will be selected in 2026 for prices taking effect in 2028, and 20 per year after that. The program is cumulative — each year adds more drugs to the list.
Combined with the out-of-pocket cap
These lower prices work alongside the $2,100 out-of-pocket cap that also took effect in 2025. Together, they provide two layers of protection: lower drug prices and a hard ceiling on what you pay. See all 2026 changes →
Ready to take the next step?
There are several free ways to get help with your Part D decisions:
You can also visit Medicare.gov or call 1-800-MEDICARE (1-800-633-4227)